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DC Field | Value | Language |
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dc.contributor.author | Gangamma, S. | |
dc.date.accessioned | 2020-03-31T08:18:41Z | - |
dc.date.available | 2020-03-31T08:18:41Z | - |
dc.date.issued | 2014 | |
dc.identifier.citation | Science of the Total Environment, 2014, Vol.488-489, 1, pp.70-74 | en_US |
dc.identifier.uri | http://idr.nitk.ac.in/jspui/handle/123456789/10175 | - |
dc.description.abstract | Components of biological origin constitute small but a significant proportion of the ambient airborne particulate matter (PM). However, their diversity and role in proinflammatory responses of PM are not well understood. The present study characterizes airborne bacterial species diversity in Mumbai City and elucidates the role of bacterial endotoxin in PM induced proinflammatory response in ex vivo. Airborne bacteria and endotoxin samples were collected during April-May 2010 in Mumbai using six stage microbial impactor and biosampler. The culturable bacterial species concentration was measured and factors influencing the composition were identified by principal component analysis (PCA). The biosampler samples were used to stimulate immune cells in whole blood assay. A total of 28 species belonging to 17 genera were identified. Gram positive and spore forming groups of bacteria dominated the airborne culturable bacterial concentration. The study indicated the dominance of spore forming and human or animal flora derived pathogenic/opportunistic bacteria in the ambient air environment. Pathogenic and opportunistic species of bacteria were also present in the samples. TNF-? induction by PM was reduced (35%) by polymyxin B pretreatment and this result was corroborated with the results of blocking endotoxin receptor cluster differentiation (CD14). The study highlights the importance of airborne biological particles and suggests need of further studies on biological characterization of ambient PM. 2014 Elsevier B.V. | en_US |
dc.title | Characteristics of airborne bacteria in Mumbai urban environment | en_US |
dc.type | Article | en_US |
Appears in Collections: | 1. Journal Articles |
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