Please use this identifier to cite or link to this item:
https://idr.l3.nitk.ac.in/jspui/handle/123456789/13193
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chia, T.S. | |
dc.contributor.author | Quah, C.K. | |
dc.contributor.author | Ooi, C.W. | |
dc.contributor.author | Garudachari, B. | |
dc.contributor.author | Isloor, N.A. | |
dc.contributor.author | Isloor, A.M. | |
dc.contributor.author | Fun, H.-K. | |
dc.date.accessioned | 2020-03-31T08:45:22Z | - |
dc.date.available | 2020-03-31T08:45:22Z | - |
dc.date.issued | 2014 | |
dc.identifier.citation | Journal of Chemical Crystallography, 2014, Vol.44, 1, pp.51-56 | en_US |
dc.identifier.uri | http://idr.nitk.ac.in/jspui/handle/123456789/13193 | - |
dc.description.abstract | Two new derivatives of semicarbazone, (E)-2-(hexan-2-ylidene) hydrazinecarboxamide and (E)-2-(heptan-2-ylidene)hydrazinecarboxamide were synthesized and characterized by IR and 1H NMR. Their crystal structures were characterized by X-ray diffraction method. Compound (I) crystallizes in triclinic P 1 ?, a = 6.7679(7) , b = 7.1912(8) , c = 9.9969(11) , ? = 108.824(2), ? = 99.398(3), ? = 92.680(2), V = 451.75(8) 3, Z = 2, R 1 = 0.043 and wR 2 = 0.140. Compound (II) crystallizes in triclinic P 1 ?, a = 6.7192(6) , b = 7.2094(6) , c = 11.2842(11) , ? = 103.303(2), ? = 106.198(2), ? = 91.219(1), V = 508.70(8) 3, Z = 2, R 1 = 0.044 and wR 2 = 0.133. Their molecules adopt a L-shape conformation with C atom in C=N double bond acting as the junction point. The C=O double bond indicate the existence of semicarbazone group in keto-like form for both compounds in their solid state. In the crystal, the carbonyl O atom for both derivatives acts as a common acceptor in the intermolecular bifurcated N-H O hydrogen bonding which linked the molecules into one-dimensional supramolecular ribbons. Antimicrobial studies by serial dilution method showed both compounds exhibit antibacterial property. Graphical Abstract: Two new semicarbazone derivatives are characterized by IR, 1H NMR and single crystal X-ray diffraction methods and their antibacterial activity was further investigated by screening against four different bacterial strains.[Figure not available: see fulltext.] 2013 Springer Science+Business Media New York. | en_US |
dc.title | Syntheses, crystal structures and antimicrobial studies of two new semicarbazone derivatives | en_US |
dc.type | Article | en_US |
Appears in Collections: | 1. Journal Articles |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.