Please use this identifier to cite or link to this item:
https://idr.l3.nitk.ac.in/jspui/handle/123456789/13305
Title: | Synthesis, characterization and their anticonvulsant, anti-inflammatory studies of some novel chromeno oxadiazoles |
Authors: | Ubaradka, S.R. Isloor, A.M. Shetty, P. Shetty, P. Isloor, N.A. |
Issue Date: | 2013 |
Citation: | Medicinal Chemistry Research, 2013, Vol.22, 3, pp.1497-1503 |
Abstract: | In this study, a series of new 1,2,4-oxadiazole derivatives containing 3,4-dihydro-2H-chromen-2-amine moiety were synthesized by efficient microwave reaction of 2-amino-N?-hydroxychroman-3-carboxamidine and suitable aldehyde. Structures of all the synthesized compounds were confirmed by spectral studies and C, H, N analyses. Newly synthesized compounds were screened for their anticonvulsant and anti-inflammatory properties. Few of the compounds exhibited excellent anticonvulsant activity as compared to the standard drug Diazepam. Also compounds have exhibited moderate anti-inflammatory activity as compared to the standard drug Diclofenac sodium. 2012 Springer Science+Business Media, LLC. |
URI: | http://idr.nitk.ac.in/jspui/handle/123456789/13305 |
Appears in Collections: | 1. Journal Articles |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.